are infants of diabetic mothers physiologically immature
What is the newborn of a diabetic mother at risk to develop?
Babies born to mothers with diabetes are at an increased risk of developing low blood sugar or hypoglycemia shortly after birth and during the first few days of life, since they are already producing an excess of insulin.
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Which of the following is a common problem in the newborn of a diabetic mother?
Infants of diabetic mothers are prone to various neonatal adverse outcomes, including metabolic and hematologic disorders, respiratory distress, cardiac disorders and neurologic impairment due to perinatal asphyxia and birth traumas, among others.
Can a diabetic mom have a healthy baby?
If you are healthy and your diabetes is well controlled when you become pregnant, you have a good chance of having a normal pregnancy and birth. Diabetes that is not well controlled during pregnancy can affect your health long-term and can also be risky for your baby.
Does insulin cause placenta to deteriorate?
Insulin is directly toxic to early placenta and elevated levels can lead to pregnancy loss, according to new research. Metformin, a low-cost medication for diabetes management, as well as diet modifications in the form of reduced carbohydrates and sugar have shown promise in potentially preventing miscarriage.
Why do babies born to diabetic mothers have respiratory distress syndrome?
Infants of a Diabetic Mother (IDMs) and RDS Respiratory distress syndrome (RDS) is a common cause of respiratory distress affect- ing newborns. RDS occurs secondary to surfactant deficiency due to inadequate production of surfactant.
Which is the most common congenital malformation in a baby of diabetic mother?
They followed 609 diabetic pregnancies and found that 3.6% of the women delivered infants with cardiovascular defects, the most common being transposition of great arteries, truncus arteriosus and tricuspid atresia. Janssen et al[18] studied 1511 PGD cases, with congenital birth defects prevalence of 7.2%.
Why do infants of diabetic mothers have polycythemia?
Polycythaemia is an important problem that is observed in some infants born to diabetic mothers: fetal hyperinsulinaemia and elevated Epo levels, due to intrauterine chronic hypoxia, may cause polycythaemia in these infants.
Why are babies of diabetic mothers Macrosomic?
In GDM, a higher amount of blood glucose passes through the placenta into the fetal circulation. As a result, extra glucose in the fetus is stored as body fat causing macrosomia, which is also called ‘large for gestational age’.
Why do infants of diabetic mothers have cardiomyopathy?
In infants of diabetic mothers, HCM is thought to arise from the effects of excess insulin. The finding of a very similar HCM in infants with congenital hyperinsulinism is consistent with a causal role for fetal hyperinsulinaemia in this cardiac abnormality.
Which major neonatal complication is carefully monitored after the birth of the infant of a diabetic mother?
After the birth of a child of the diabetic mother, the newborn should be treated with special care. The clinical condition of the newborn baby must be assessed very carefully and its vital functions in the first days after birth should be monitored thoroughly. Hypoglycemia.
Why do babies of diabetic mothers have hypoglycemia?
An IDM is more likely to have periods of low blood sugar (hypoglycemia) shortly after birth, and during first few days of life. This is because the baby has been used to getting more sugar than needed from the mother. They have a higher insulin level than needed after birth. Insulin lowers the blood sugar.
Can insulin needles hurt baby?
Insulin is injected into fatty tissue. It does not cross the placenta. That means it does not affect your baby the way taking a pill would.
When is insulin resistance highest in pregnancy?
At 12–14 weeks’ gestation, insulin sensitivity is slightly increased but then declines for the rest of the pregnancy, with insulin resistance being highest late in the third trimester.
Does maternal diabetes affect the fetal lung maturity?
Poorly controlled maternal diabetes in pregnancy may delay fetal pulmonary maturation. However, diabetic women with good glycemic control have fetal lung maturation at the same gestational age as nondiabetic women.
How common are birth defects in diabetic mothers?
Ninety-three percent of the birth defects weren’t associated with maternal diabetes. Two percent of the children with single birth defects were born to mothers who had diabetes before their pregnancy, while 5% of those born with multiple defects were born to diabetic moms.
Does insulin cause birth defects?
Gestational diabetes affects the mother in late pregnancy, after the baby’s body has been formed, but while the baby is busy growing. Because of this, gestational diabetes does not cause the kinds of birth defects sometimes seen in babies whose mothers had diabetes before pregnancy.
Why do infants of diabetic mothers have hypocalcemia?
End organ responsiveness was shown by a calcemic and phosphaturic response to exogenous parathormone. It is speculated that relative maternal hyperparathyroidism leading to fetal hypoparathyroidism may be a factor in the pathogenesis of neonatal hypocalcemia in infants of diabetic mothers.
What is neonatal polycythemia?
Neonatal polycythemia is characterized by a venous hematocrit (hct) that greatly exceeds normal values for gestational and postnatal age. This condition affects approximately 1 to 5 percent of newborns.
What are two conditions that cause polycythemia?
Secondary polycythemia most often develops as a response to chronic hypoxemia, which triggers increased production of erythropoietin by the kidneys. The most common causes of secondary polycythemia include obstructive sleep apnea, obesity hypoventilation syndrome, and chronic obstructive pulmonary disease (COPD).
What is the most common complication for the mother of an oversized fetus?
Possible maternal complications of fetal macrosomia might include: Labor problems. Fetal macrosomia can cause a baby to become wedged in the birth canal (shoulder dystocia), sustain birth injuries, or require the use of forceps or a vacuum device during delivery (operative vaginal delivery).
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