are diuretics used to treat underlying causes of diabetes

are diuretics used to treat underlying causes of diabetes

Which diuretic is good for diabetics?

We conclude that Indapamide is safe and effective in lowering blood pressure and contributes to better control of blood glucose and lipid levels in diabetic and dyslipidemic patients, compared to standard diuretics.

What conditions are diuretics used for?

Diuretics, also called water pills, are a common treatment for high blood pressure. Find out how they work and when you might need them. Diuretics, sometimes called water pills, help rid your body of salt (sodium) and water.

Do diuretics cause diabetes?

Prolonged thiazide diuretic therapy can lead to glucose intolerance and may occasionally precipitate diabetes mellitus. Short-term metabolic studies, epidemiologic studies, and a variety of clinical trials suggest a connection between ongoing thiazide diuretic use and the development of type 2 diabetes.

Does chlorthalidone cause diabetes?

Recent data from ALLHAT indicate there is no increased risk for cardiovascular outcomes in those with chlorthalidone induced hyperglycemia or diabetes [9].

Why does hydrochlorothiazide cause diabetes?

It is possible that hydrochlorothiazide increases the production of glucose from the liver, and because beta-blockers limit the absorption of glucose into cells, the use of these medicines in tandem can raise glucose levels significantly enough to cause diabetes.

Are diuretics bad for kidneys?

Diuretics. Doctors use these medicines, also known as water pills, to treat high blood pressure and some kinds of swelling. They help your body get rid of extra fluid. But they can sometimes dehydrate you, which can be bad for your kidneys.

What is the safest diuretic?

TUESDAY, Feb. 18, 2020 (HealthDay News) — Patients taking a common diuretic to help lower blood pressure may be better off with a similarly effective but safer one, a new study suggests. Current guidelines recommend the drug chlorthalidone (Thalitone) as the first-line diuretic.

How does thiazide diuretics cause diabetes?

These data suggest that thiazide-induced hypokalemia is associated with increased blood glucose. Treatment of thiazide-induced hypokalemia may reverse glucose intolerance and possibly prevent the future development of diabetes.

How much do diuretics raise blood sugar?

When ALLHAT investigators specifically looked at study participants who had diabetes, they found that these people tended to do well on thiazide diuretics but also had, on average, a small increase in blood glucose (5 mg/dl). Many other large studies have also noted this effect.

Can diabetes caused by statins be reversed?

As of yet, we do not know whether statin-induced diabetes is reversible akin to statin-induced cognitive deficits, which are reversed upon cessation of therapy as clearly documented in the US FDA expanded safety label statement.

Does atorvastatin cause diabetes?

High-dose atorvastatin was linked to a 37 percent increased diabetes risk, the study found. Based on these findings, physicians will have to weigh risks versus benefits before prescribing statins, said Dr.

Can statins cause diabetes?

It’s possible your blood sugar (blood glucose) level may increase when you take a statin, which may lead to developing type 2 diabetes. The risk is small but important enough that the Food and Drug Administration (FDA) has issued a warning on statin labels regarding blood glucose levels and diabetes.

Is hydrochlorothiazide safe for diabetes?

Current use of hydrochlorothiazide is limited to low doses due to the known risk of hyperglycemia and diabetes in patients. A recent study combined HCTZ with amiloride to neutralize potassium loss and therefore neutralize glucose changes in patients.

Can you take HCTZ if you have diabetes?

While thiazide diuretics are still a recommended medication of hypertension therapy for type 2 diabetes, treatment with low-dose HCTZ should be attempted to evaluate the effectiveness and adverse metabolic effects.

Can hydrochlorothiazide cause hyperglycemia?

It was found that hydrochlorothiazide raised fasting glucose concentration significantly; propranolol alone caused an insignificant rise of glucose, but significantly aggravated the effect of hydrochlorothiazide with an additive interaction.

Who should not take chlorthalidone?

You should not use chlorthalidone if you are allergic to it, or if: you are unable to urinate; or. you are allergic to sulfa drugs.

Which is safer chlorthalidone or hydrochlorothiazide?

HCTZ and chlorthalidone are both safe and cheap first-line blood pressure medications, but the evidence is clear—chlorthalidone is better.

Is chlorthalidone safe for kidneys?

Chlorthalidone increased the risk of the following side effects when compared to hydrochlorothiazide: Low potassium levels (hypokalemia), nearly three times greater risk. Low sodium levels (hyponatremia), 31 percent greater risk. Acute kidney failure, 37 percent greater risk.

Who should not take hydrochlorothiazide?

You should not use hydrochlorothiazide if you are unable to urinate. Before using hydrochlorothiazide, tell your doctor if you have liver disease, kidney disease, glaucoma, asthma or allergies, gout, diabetes, or if you are allergic to sulfa drugs or penicillin.

What is the difference between chlorthalidone and hydrochlorothiazide?

Chlorthalidone produces slightly greater reductions in blood pressure compared with hydrochlorothiazide (HCTZ), but it is associated with greater declines in serum potassium levels.