are diabetics more prone to oral lichen planus

are diabetics more prone to oral lichen planus

Can metformin cause Oral Lichen Planus?

In addition, cutaneous side-effects such as leukocytoclastic vasculitis, bullous pemphigoid, psoriasiform drug eruption, lichen planus and acute alopecia have been associated with metformin use and are discussed in the article.

Who is at risk for lichen planus?

Lichen planus usually affects men and women in middle age. Equal numbers of men and women get lichen planus of the skin, but women are twice as likely to get oral (inside the mouth) lichen planus. The disease is rare in people who are very young or very old.

Who Gets Oral Lichen Planus?

Anyone can develop oral lichen planus, but it’s more common in middle-aged women. Some factors may increase your risk of developing oral lichen planus, such as having a disorder that lowers your immunity or taking certain medications, though more research is needed.

What diabetic drugs cause lichen planus?

Among the oral hypoglycemic drugs, sulfonylureas have been reported in association with lichen planus [2].

Can diabetes cause lichen sclerosus?

A review of 76 patients with lichen sclerosus et atrophicus reveals a number of cases in which this disorder is associated with glucose intolerance or diabetes mellitus. The performance of an oral glucose tolerance test is therefore recommended for all patients with lichen sclerosus et atrophicus.

What autoimmune disease causes lichen planus?

Lichen planus (LP) is thought to be an autoimmune disorder in patients with a genetic predisposition but may be caused by drugs or be associated with disorders such as hepatitis C. LP is characterized by recurrent, pruritic papules that are polygonal, flat-topped, and violaceous and can coalesce into plaques.

What mouthwash is best for Oral lichen planus?

According to the results of the present study, either zinc mouthwash with fluocinolone ointment or fluocinolone ointment separately was effective in decreasing lesion surface area, pain, and irritation of erosive oral lichen planus.

What is the best mouthwash for lichen planus?

Clobetasol oral rinse is a topical steroid commonly used to treat oral lichen planus.

Is lichen planus a symptom of lupus?

Lupus erythematosus lichen planus (LE-LP) overlap syndrome remains an uncommon diagnostic entity, combining both the histologic and clinical features of lupus erythematosus and lichen planus. A rare and challenging diagnosis, clinicopathologic correlation is essential for accurate and timely identification.

What foods trigger oral lichen planus?

They’ll likely hurt the most when you eat or drink foods that are spicy, salty, acidic (orange juice, tomatoes), or alcoholic. Crispy treats and drinks with caffeine can also cause problems. Your doctor can diagnose oral lichen planus by taking a small piece of skin from inside your mouth.

Should oral lichen planus be biopsied?

Lichen planus can be diagnosed clinically in classic cases, although biopsy is often helpful to confirm the diagnosis and is required for more atypical presentations. A 4-mm punch biopsy should be adequate on the skin or in the mouth.

Does metformin cause Lichenoid reaction?

Case reports of possible reactions to metformin include erythema multiforme, lichen planus, rosacea, and pseudoporphyria [3–6]. The second most common drug-induced cutaneous reactions are fixed-drug eruptions (FDEs) [7].

What are the side effects of metformin?

Nausea, vomiting, stomach upset, diarrhea, weakness, or a metallic taste in the mouth may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. If stomach symptoms return later (after taking the same dose for several days or weeks), tell your doctor right away.

Does Ozempic cause lichen planus?

Phenothiazine derivatives. Anti-convulsants – carbamazepine, phenytoin. Medicines to treat tuberculosis. Antifungal medication – ketoconazole.

Can lichen planus cause fatigue?

Immune modulators – such as imiquimod and levamisole may be advised by a specialist if lichen planus is severe. These work with the body’s immune system to help fight damage to the skin. Skin irritation, headache, nausea and tiredness can be side-effects.

What’s the difference between lichen planus and lichen sclerosus?

The main difference between the two conditions is that LP has a propensity to involve the mucous membranes including the mouth and vagina which are rarely affected in LS. First-line treatment for LS is a super-potent topical corticosteroid ointment which has a high response rate.

What autoimmune disease causes lichen sclerosus?

The most common autoimmune diseases associated with lichen sclerosus are autoimmune thyroiditis, alopecia areata, vitiligo, and pernicious anemia. In addition to an autoimmune factor, it appears that genetics has a pathogenetic role as well.

Is Oral Lichen Planus precancerous?

Oral lichen planus (OLP) is a common mucosal condition that is considered premalignant by some, although others argue that only lichenoid lesions with dysplasia are precancerous.

Can Oral Lichen Planus affect the throat?

Oral lichen planus occurs most often on the inside of your cheeks but also can affect your gums, tongue, lips and other parts of your mouth. Oral lichen planus sometimes involves your throat or esophagus. While oral lichen planus usually begins during midlife, it can occur at any age.

Is Lichen Planus linked to other diseases?

Lichen planus is a cell-mediated immune response of unknown origin. It may be found with other diseases of altered immunity, such as ulcerative colitis, alopecia areata, vitiligo, dermatomyositis, morphea, lichen sclerosis, and myasthenia gravis.