are diabetics more prone to lichen planus

are diabetics more prone to lichen planus

Does metformin cause lichen planus?

In addition, cutaneous side-effects such as leukocytoclastic vasculitis, bullous pemphigoid, psoriasiform drug eruption, lichen planus and acute alopecia have been associated with metformin use and are discussed in the article.

What diseases are linked to lichen planus?

Lichen planus is a cell-mediated immune response of unknown origin. It may be found with other diseases of altered immunity; these conditions include ulcerative colitis, alopecia areata, vitiligo, dermatomyositis, morphea, lichen sclerosis, and myasthenia gravis.

What autoimmune disease causes lichen planus?

Lichen planus (LP) is thought to be an autoimmune disorder in patients with a genetic predisposition but may be caused by drugs or be associated with disorders such as hepatitis C. LP is characterized by recurrent, pruritic papules that are polygonal, flat-topped, and violaceous and can coalesce into plaques.

Can diabetes cause lichen planus?

The prevalence reported ranges from 1.6% to 37.7% with a relative risk of 2.432. Ten studies assessed the prevalence of lichen planus among patients with diabetes mellitus which showed a prevalence of lichen planus ranging from 0.5% to 6.1% with a relative risk of 1.4.

What diabetic drugs cause lichen planus?

Among the oral hypoglycemic drugs, sulfonylureas have been reported in association with lichen planus [2].

What causes lichen planus to flare up?

It’s possible that, in some people, oral lichen planus may be triggered by certain medications, mouth injury, infection or allergy-causing agents such as dental materials. Stress may be involved in symptoms becoming worse or recurring.

Is lichen planus a symptom of lupus?

Lupus erythematosus lichen planus (LE-LP) overlap syndrome remains an uncommon diagnostic entity, combining both the histologic and clinical features of lupus erythematosus and lichen planus. A rare and challenging diagnosis, clinicopathologic correlation is essential for accurate and timely identification.

What medications can trigger lichen planus?

Oral lichenoid drug reactions may be triggered by systemic drugs including NSAIDs, beta-blockers, sulfonylureas, some ACE inhibitors, and some antimalarials. In patients with oral lichenoid lesions, be alert for any systemic drug as a cause.

Is sun good for lichen planus?

If the lichen planus is on the regular skin and not very severe, treatment is often not needed. If the lichen planus is caused by the sun (some cases of lichen planus pigmentosus), a strong sunscreen (sun protection factor [SPF] 50 or higher) should be used daily.

Can lichen planus cause fatigue?

Immune modulators – such as imiquimod and levamisole may be advised by a specialist if lichen planus is severe. These work with the body’s immune system to help fight damage to the skin. Skin irritation, headache, nausea and tiredness can be side-effects.

Does Vitamin D Help lichen planus?

The results showed that vitamin D supplementation in group I oral lichen planus patients had marked improvement in burning sensation.

Is there a link between diabetes and lichen sclerosus?

A review of 76 patients with lichen sclerosus et atrophicus reveals a number of cases in which this disorder is associated with glucose intolerance or diabetes mellitus. The performance of an oral glucose tolerance test is therefore recommended for all patients with lichen sclerosus et atrophicus.

Does metformin cause Lichenoid reaction?

Case reports of possible reactions to metformin include erythema multiforme, lichen planus, rosacea, and pseudoporphyria [3–6]. The second most common drug-induced cutaneous reactions are fixed-drug eruptions (FDEs) [7].

What are the side effects of metformin?

Nausea, vomiting, stomach upset, diarrhea, weakness, or a metallic taste in the mouth may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. If stomach symptoms return later (after taking the same dose for several days or weeks), tell your doctor right away.

Does Ozempic cause Lichen Planus?

Phenothiazine derivatives. Anti-convulsants – carbamazepine, phenytoin. Medicines to treat tuberculosis. Antifungal medication – ketoconazole.

What happens if lichen planus goes untreated?

The affected skin might stay slightly darker even after the rash clears up, especially in dark-skinned people. Oral lichen planus increases the risk of oral cancer. Left untreated, lichen planus of the ear canal may lead to hearing loss.

Is lichen planus cancerous?

Background: Oral lichen planus (OLP) and oral lichenoid lesions (OLL) are considered potentially malignant disorders with a cancer incidence of around 1% of cases, although this estimation is controversial.

Is lichen planus autoimmune?

Lichen planus is a chronic, inflammatory, autoimmune disease that affects the skin, oral mucosa, genital mucosa, scalp, and nails.

What is the difference between lupus and lichen planus?

Lichen planus (LP) is a chronic inflammatory mucocutaneous disorder with unknown etiology. Systemic lupus erythematosus (SLE) is known as a prototypic autoimmune disease. Cytokines play a key role in the pathogenesis of both diseases.

Does lichen planus show up in blood test?

Your healthcare provider or dentist may diagnose lichen planus based on the changes on your skin or in your mouth. To make sure of the diagnosis, you may need these tests: Blood test. This can rule out other causes of your symptoms.